The human norepinephrine transporter (hNET) is a transmembrane protein responsible for the uptake of norepinephrine into the synaptic terminals of the central and peripheral nervous systems and into neuroendocrine adrenal chromaffin cells. Notably, neural crest tumors, such as neuroblastoma, paraganglioma and pheochromocytoma, are often characterized by high hNET expression1. Iodine-123 labeled meta-iodobenzyl guanidine ([123I]mIBG) has long been employed for hNET imaging.
S.R.Y. (Specialized Medical Services) is an Israeli company that manufactures and develops radiopharmaceuticals for diagnosis, treatment and medical research. The company operates the cyclotron unit at Hadassah Ein Kerem Hospital and produces medical isotopes in an advanced nuclear pharmacy.
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